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PLA2R1 Monoclonal / Unconjugated / CL0474

Product Details

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-52933 (View supplier product page)
	Size	0.1 ml
	Price	$519.00
	Antigen	PLA2R1
	Clone	CL0474
	Host	Mouse
	Isotype	IgG1
	Conjugate	Unconjugated
	Target Species	Human
	Applications	WB, IHC, ICC/IF, IHC-P
	Description	Specificity of human PLA2R1 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

About PLA2R1 and Purified

	PLA2R1	This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]

Images

		Immunohistochemistry-Paraffin: PLA2R1 Antibody (CL0474) [NBP2-52933] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
		Immunocytochemistry/Immunofluorescence: PLA2R1 Antibody (CL0474) [NBP2-52933] - Staining of HeLa cells using the Anti-PLA2R1 monoclonal antibody, showing specific staining in the cytosol in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available). Antibody staining is shown in green.
		Immunohistochemistry-Paraffin: PLA2R1 Antibody (CL0474) [NBP2-52933] - Staining in human kidney and pancreas tissues. Corresponding PLA2R1 RNA-seq data are presented for the same tissues.
		Western Blot: PLA2R1 Antibody (CL0474) [NBP2-52933] - Analysis in human kidney tissue.
		Immunohistochemistry-Paraffin: PLA2R1 Antibody (CL0474) [NBP2-52933] - Staining of human kidney with membranous nephropathy shows strong membranous immunoreactivity in renal glomeruli.
		Immunocytochemistry/Immunofluorescence: PLA2R1 Antibody (CL0474) [NBP2-52933] - Staining of MCF7 cells using the Anti-PLA2R1 monoclonal antibody, showing only weak staining in cytosol. MCF7 cells serves as a negative control based on RNA-seq values. Microtubule- and nuclear probes are visualized in red and blue, respectively (where a
		Immunocytochemistry/Immunofluorescence: PLA2R1 Antibody (CL0474) [NBP2-52933] - Staining of BJ cells using the anti-PLA2R1 monoclonal antibody, showing specific staining in the cytosol in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available). Antibody staining is shown in green.
		Immunohistochemistry-Paraffin: PLA2R1 Antibody (CL0474) [NBP2-52933] - Staining of human kidney shows weak membranous positivity in cells in glomeruli.

Citations

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