p27 KIP 1 Monoclonal / CF660R / SX53G8

Product Details
Supplier Biotium
Catalog #: BNC610669-100 (View supplier product page)
Size 100 μl
Price $157.00
Antigen p27 KIP 1
Clone SX53G8
Host Mouse
Isotype IgG1 κ
Conjugate CF660R
Target Species Human, Monkey, Mouse, Rat
Applications IF, IHC-P, FC, WB
Description p27 / KIP1 Monoclonal Mouse Antibody (SX53G8)
About p27 KIP 1 and CF660R
p27 KIP 1 This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
CF660R CF®660R from Biotium is a fluorophore with an excitation peak at 662 nm and an emission peak at 682 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 660.
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CF660R Excitation and Emission Spectra