FGF-R4 / Alexa Fluor 647 / 249

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-89557AF647 (View supplier product page)
Size 100 μl
Price $549.00
Antigen FGF-R4
Clone 249
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 647
Target Species Human
Applications ELISA
Description FGFR4 Antibody (249) [Alexa Fluor® 647]
About FGF-R4 and Alexa Fluor 647
FGF-R4 The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra