CD299 / DyLight 755 / 120604

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB162Z (View supplier product page)
Size 500 μl
Price $759.00
Antigen CD299
Clone 120604
Host Mouse
Isotype IgG2b
Conjugate DyLight 755
Target Species Human
Applications FC
Description DC-SIGNR/CD299/CLEC4M Antibody (120604) [DyLight 755]
About CD299 and DyLight 755
CD299 This gene encodes a C-type lectin that functions in cell adhesion and pathogen recognition. This receptor recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including tuberculosis mycobacteria, and viruses including Ebola, hepatitis C, HIV-1, influenza A, West Nile virus and the SARS-CoV acute respiratory syndrome coronavirus. The protein is organized into four distinct domains: a C-terminal carbohydrate recognition domain, a flexible tandem-repeat neck domain of variable length, a transmembrane region and an N-terminal cytoplasmic domain involved in internalization. This gene is closely related in terms of both sequence and function to a neighboring gene, CD209 (Gene ID: 30835), also known as DC-SIGN. The two genes differ in viral recognition and expression patterns, with this gene showing high expression in endothelial cells of the liver, lymph node and placenta. Polymorphisms in the tandem repeat neck domain are associated with resistance to SARS infection. [provided by RefSeq, May 2020]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

DyLight 755 Excitation and Emission Spectra