GM-CSF / DyLight 405 / 6804

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB615E (View supplier product page)
Size 0.1 ml
Price $609.00
Antigen GM-CSF
Clone 6804
Host Mouse
Isotype IgG1
Conjugate DyLight 405
Target Species Human
Applications ELISA, ICFC
Description GM-CSF Antibody (6804) [DyLight 405]
About GM-CSF and DyLight 405
GM-CSF The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis. [provided by RefSeq, Aug 2020]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra