CD299 / APC / 16E7
CD299 / APC / 16E7
Product Details
Supplier | Thermo Fisher Scientific | |
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Catalog #: | 17-2999-41 (View supplier product page) | |
Size | 25 Tests | |
Price | $118.00 | |
Antigen | CD299 | |
Clone | 16E7 | |
Host | Mouse | |
Isotype | IgG2a κ | |
Conjugate | APC | |
Target Species | Human | |
Applications | FC | |
Description | CD299 (DC-SIGN/L) Monoclonal Antibody (16E7), APC, eBioscience™ |
About CD299 and APC
CD299 | This gene encodes a C-type lectin that functions in cell adhesion and pathogen recognition. This receptor recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including tuberculosis mycobacteria, and viruses including Ebola, hepatitis C, HIV-1, influenza A, West Nile virus and the SARS-CoV acute respiratory syndrome coronavirus. The protein is organized into four distinct domains: a C-terminal carbohydrate recognition domain, a flexible tandem-repeat neck domain of variable length, a transmembrane region and an N-terminal cytoplasmic domain involved in internalization. This gene is closely related in terms of both sequence and function to a neighboring gene, CD209 (Gene ID: 30835), also known as DC-SIGN. The two genes differ in viral recognition and expression patterns, with this gene showing high expression in endothelial cells of the liver, lymph node and placenta. Polymorphisms in the tandem repeat neck domain are associated with resistance to SARS infection. [provided by RefSeq, May 2020] | |
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APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
Reviews & Ratings
APC Excitation and Emission Spectra
$118.00
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