Caspase 3 / Janelia Fluor 646 / 31A893

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-56709JF646 (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen Caspase 3
Clone 31A893
Host Mouse
Isotype IgG
Conjugate Janelia Fluor 646
Target Species Human
Applications IHC, ICC/IF, IHC-P
Description Mouse Caspase-3 antibody [Janelia Fluor 646] reacts with Human
About Caspase 3 and Janelia Fluor 646
Caspase 3 The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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Janelia Fluor 646 Excitation and Emission Spectra