FluoroFinder

	Supplier	Biorbyt
	Catalog #:	orb66916-100ul (View supplier product page)
	Size	100 μl
	Price	$657.00
	Antigen	BLM
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human, Mouse
	Applications	WB
	Description	Rabbit polyclonal to BLM.BLM (Bloom syndrome protein) is a magnesium-dependent and ATP-dependent DNA-helicase. BLMunwinds both single-and double-stranded DNA from 3 to 5 for DNA replication and repair. Defectsin BLM cause Bloom syndrome.

	BLM	The Bloom syndrome is an autosomal recessive disorder characterized by growth deficiency, microcephaly and immunodeficiency among others. It is caused by homozygous or compound heterozygous mutation in the gene encoding DNA helicase RecQ protein on chromosome 15q26. This Bloom-associated helicase unwinds a variety of DNA substrates including Holliday junction, and is involved in several pathways contributing to the maintenance of genome stability. Identification of pathogenic Bloom variants is required for heterozygote testing in at-risk families. [provided by RefSeq, May 2020]