Loading the Dye Directory…

Hoechst (33342)

Hoechst (33342) (Ex-Max 361 nm/Em-Max 497 nm)

Hoechst (33342) is a cell-permeant, fluorogenic nucleic acid stain. It has an excitation peak at 361 nm and an emission peak at 497 nm. It is useful in counter-staining nuclei in both flow cytometry and microscopy.

Excitation & emission spectra

400450500550600650700750800

Key facts

Excitation maximum
361 nm
Emission maximum
497 nm
Optimal laser line
355
Optimal filter
450/50
Commercial antibodies
7 from 4 suppliers

Hoechst (33342) has an excitation maximum at 361 nm and an emission maximum at 497 nm, a Stokes shift of 136 nm. It is optimally excited by the 355 laser line.

Frequently asked questions

What is Hoechst (33342)?
Hoechst (33342) is a cell-permeant, fluorogenic nucleic acid stain. It has an excitation peak at 361 nm and an emission peak at 497 nm. It is useful in counter-staining nuclei in both flow cytometry and microscopy.
What laser excites Hoechst (33342)?
Hoechst (33342) is optimally excited by the 355 laser line. Its excitation maximum is 361 nm.
What filter should I use to detect Hoechst (33342)?
A 450/50 filter captures the peak of the Hoechst (33342) emission near 497 nm with minimal spillover.
How many antibodies are available conjugated to Hoechst (33342)?
FluoroFinder tracks 7 commercially available Hoechst (33342) conjugates, searchable by target, clone, host and application.